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Welcome to East Bay Cardiac Surgery Center

East Bay Cardiac Surgery CenterEast Bay Cardiac Surgery Center is a state-of-the-art facility conveniently located in Oakland, CA. Our experienced cardiothoracic surgeons provide a wide variety of cardiac services, including Minimal Incision Valve Surgery (MIVS), thoracic oncology, heart valve replacement, mitral and aortic heart valve repair, coronary artery bypass surgery (CABS), and more. Our emphasis is on providing the best quality technical interventions combined with addressing the individual needs of each patient. We are dedicated to quality patient care and proud of the outstanding results we continue to achieve.

Our cardiothoracic surgeons have been recognized in various publications for their excellence in cardiovascular health, and our surgery center was rated one of the best statewide by the San Diego Union Tribune. For more information about the accomplishments and recognitions received by our experienced staff, please visit the Achievements page.

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Dr. Khan

Junaid H. Khan, M.D., Surgeon

 Dr. Khan is a graduate of the University of California, Los Angeles School of Medicine. He completed his residency in general surgery, cardiac surgery, and thoracic surgery at the University of California in San Francisco. Dr. Khan worked for two years in the research lab at UCSF. He specializes in adult cardiac surgery and thoracic surgery, including coronary artery bypass grafting and minimally invasive valve surgery. He has a particular interest in endoscopic mitral valve repair.

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Dr. Stanten

Russell D. Stanten, M.D., Surgeon

Dr. Stanten attended Baylor College of Medicine in Houston, Texas. His internship and residency were completed at the University of California, Davis Medical Center. His fellowship in cardiothoracic surgery was fulfilled at Brigham & Women’s Hospital, Boston Massachusettes. Dr. Stanten specializes in adult cardiac and thoracic surgery, including coronary artery bypass grafting, heart valve replacement, heart valve repair, lung cancer, esophageal surgery, and minimally invasive valve surgery.

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Services

East Bay Cardiac Surgery Center provides the following surgical services:

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East Bay Cardiac Surgery Center
3300 Webster Street, Suite 500
Oakland, CA  94610-3149

Telephone - (510) 465-6600
Fax - (510) 839-0806

E-mail - This email address is being protected from spambots. You need JavaScript enabled to view it.

The office is open from 9:00 a.m. to 5:00 P.M., Monday through Friday

Our location is in the Broadway Webster Medical Plaza. Validated parking is available in our office building. The garage entrance is on Hawthorne Avenue. Please bring your parking ticket to the office for validation.

Schedule an appointment today for a consultation with one of our experienced surgeons. We accept most major forms of insurance. If our clinic is not a preferred provider with your insurance policy, we will work with you to ensure you get the most out of our services.

(11-28) 11:59 PST SAN FRANCISCO -- A new generation of blood thinners offers potentially millions of people alternatives to

warfarin, a 60-year-old anticlotting drug derived from rat poison that can be difficult for patients to manage and requires

frequent monitoring.

While these new drugs have great promise, they come with a potentially fatal flaw: If a patient starts bleeding seriously, there's no simple

way to stop it.

"It's groundbreaking and it's exciting. We're thrilled to have these medications available to us," said Dr. Matthew DeVane, a Walnut Creek

cardiologist who serves as board director for the American Heart Association's East Bay region. "The downside of the new ones is we don't

have an antidote to reverse the blood thinning effects."

A South San Francisco biotechnology company is working on that.

Portola Pharmaceuticals Inc. earlier this month received an undisclosed sum of money from large drug manufacturers Bristol-Myers

Squibb and Pfizer Inc. to test an agent that could reverse the effects of these new anticoagulants in the event of bleeding from injury,

surgery or some other cause.

"It's a very unique and creative deal," said Mardi Dier, chief financial officer of Portola, which at the same time is developing its own

anticoagulant. "This is a way for them (the big drug companies) to have some input in how their drugs will work with the antidote. It

really validates the importance of the antidote."

Tames swelling, clots

Anticoagulants have long been prescribed to heart attack and stroke patients to prevent swelling and blood clots. While often referred to

as blood thinners, they don't really thin the blood. They decrease the blood's ability to clot, which prevents harmful clots from blocking

blood vessels and causing heart attacks or stroke.

The most widely prescribed anticoagulant, warfarin, sold under the brand name Coumadin, was originally developed as a rat poison, and

is now one of the most frequently prescribed medications in the United States, with nearly 18 million prescriptions dispensed annually.

Despite its popularity, the drug isn't for some patients because it has numerous drug and food interactions and requires frequent blood

tests to monitor its levels.

"Once you get to a steady state on Coumadin, you only have to check once a month. The problem is that patients don't always go to the

lab every month," DeVane said.

But it has advantages in that it's effective and cheap, and has an antidote. The antidote, vitamin K, allows the blood to clot if administered

promptly by injection or orally.

The new generation of blood thinners in recent years is expected to grab a share of a market that is estimated at around $5 billion a year

worldwide and is expected to reach $20 billion by 2020.

Pradaxa approved

Pradaxa, a twice-daily pill from Boehringer Ingelheim, received approval from the U.S. Food and Drug Administration in October 2010

for prevention of strokes in patients with atrial fibrillation, the most common type of irregular heartbeat.

In November 2011, the FDA approved another drug for atrial fibrillation called Xarelto, which Johnson & Johnson developed with Bayer.

It can be taken just once a day. The drug has since received approval to treat additional conditions, including deep vein thrombosis, which

develops when clots form in deep veins, most commonly in the leg.

Bristol-Myers Squibb and Pfizer are awaiting FDA approval for their jointly developed drug, Eliquis, which works much like Xarelto.

Portola is also developing its own version of an anticoagulant directed at seriously ill patients who have difficulty moving.

While none of these new drugs has a reversal agent, most of the concern has been directed at Pradaxa. The drug has been around the

longest and has been the target of a number of lawsuits from the families of patients who have died from uncontrolled bleeding.

All anticoagulants carry a risk of bleeding, but the newer drugs are drawing attention to the problem even though some of the latest

studies have shown that the risk of bleeding while on these drugs is no higher than for patients on warfarin.

The number of serious adverse drug events reported to the FDA - those causing injury, disability or death - has increased 90 percent

over the past four years, according to the nonprofit Institute for Safe Medication Practices. The group attributed part of those increases

to the new anticoagulants.

In its 2011 report, the nonprofit said 542 reports of deaths associated with Pradaxa were reported to the FDA last year. The number of

deaths topped all other medicines, including warfarin, the second most frequently reported drug for serious adverse effects, but with

72 deaths.

Information for Xarelto was not yet available in 2011, but the nonprofit's October report found the new drug accounted for 158 serious

adverse events in the first quarter of the year. In addition, the report points out that these new-generation coagulants cost about 15

times as much as Coumadin. Xarelto and Pradaxa cost about $3,000 a year, versus about $200 for the generic version of Coumadin.

Hope with antidote

Portola hopes to prevent such problems with its antidote, which will be designed to work for Xarelto, Eliquis and the company's own

investigative anticoagulant. The antidote won't work on Pradaxa because that drug works slightly differently. Portola's Dier said the

collaboration with the big drug manufacturers will start before the end of the year.

Doctors say that an antidote would offer peace of mind, but some are not ready to replace their faithful standby with these newcomers.

Dr. Junaid Khan, director of cardiovascular services at Alta Bates Summit Medical Center in Oakland and Berkeley, said he's concerned

that these newer drugs are eliminated through the kidneys, which could cause problems in an older patient population prone to

kidney disease.

"The medical world is still learning how to deal with these drugs," Khan said. "I still truly do not know where they fit in, and we definitely

try to use them on patients who have a problem with Coumadin, but I'm not convinced it's the first line to replace Coumadin."

Victoria Colliver is a San Francisco Chronicle staf writer. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

© 2013 Hearst Communications Inc.

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East Bay Cardiac Achievements

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New Prescription Blood Thinner Options

(11-28) 11:59 PST SAN FRANCISCO -- A new generation of blood thinners offers potentially millions of people alternatives to warfarin, a 60-year-old anticlotting drug derived from rat poison that can be...

Read more

Regionally & Nationally recognized for excellence

Regionally & Nationally recognized for excellence

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San Jose Mercury News 07/26/08 State Targets Trans Fats

San Jose Mercury News 07/26/08 State Targets Trans Fats

State targets trans fats FIRST IN U.S.: GOVERNOR SIGNS CALIFORNIA BAN By Pete Carey Mercury News Article Launched 07/26/08 01:31:21 AM PDT California on Friday became the first state in the country to...

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The San Diego Union Tribune - 01/09/08

The San Diego Union Tribune - 01/09/08

The San Diego Union Tribune - 01/09/08

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